Entrepreneurs

Biome Makers — The Startup Transforming Agriculture Through Soil Microbiomes

How a Spanish agri-tech company is helping farmers improve crop yields with microbiome data

Leah Rosenfeld
April 25, 2026 · 3 min read
Biome Makers — The Startup Transforming Agriculture Through Soil Microbiomes

Biome Makers – Science Meets Agriculture

Founded in 2015, Biome Makers is a Madrid-based agri-tech startup that leverages microbiome analysis to optimize soil health and improve crop productivity. By analyzing the microbial communities in soil, the company provides data-driven insights and recommendations to farmers, enabling them to make precise decisions on fertilization, crop rotation, and land management.

Biome Makers’ mission is to bring science and technology to farming, helping farmers produce more efficiently while reducing environmental impact.

Founding Story

Biome Makers was founded by José Luis García and César Pascual, scientists with backgrounds in microbiology, bioinformatics, and agriculture.

The founders observed that traditional farming methods often overlook the critical role of soil microbiomes. They envisioned a platform that translates complex microbial data into actionable insights for farmers worldwide.

Funding and Growth Milestones

Biome Makers has raised capital to expand its technology and global reach:

  • 2016: Seed funding of €1 million, focused on building the microbiome analysis platform.
  • 2018: Series A funding of €5 million, enabling expansion into Europe and North America.
  • 2021: Series B funding of €12 million, scaling operations to Latin America and improving AI-powered analytics.
  • 2023: Over 2,000 farms in 15+ countries use Biome Makers’ platform to optimize soil management.

Biome Makers is now recognized as a leading agri-tech startup integrating microbiome science with practical farming solutions.

Business Model and Technology

Biome Makers combines microbiology, genomics, and AI to provide actionable insights:

  • Soil Microbiome Analysis: Collects soil samples and sequences microbial DNA to assess soil health.
  • AI-Powered Recommendations: Uses machine learning to provide guidance on crop selection, soil amendments, and sustainability practices.
  • B2B Model: Primarily serves farmers, agronomists, and agricultural cooperatives.
  • Revenue Streams: Subscription-based platform fees and consulting services.

By turning complex microbiome data into actionable farming decisions, Biome Makers helps farmers increase yields while minimizing environmental impact.

Market Impact

Biome Makers has had a significant impact on agriculture and sustainability:

  • Increased Productivity: Helps farmers optimize inputs for higher yields.
  • Sustainable Practices: Encourages environmentally friendly farming by reducing unnecessary fertilizer use.
  • Global Reach: Provides soil health solutions for diverse crops in multiple regions.
  • Innovation Leadership: Pioneers the integration of microbiome science with AI in agriculture.

The company demonstrates how data-driven solutions can transform traditional industries like agriculture.

Challenges and Controversies

Biome Makers faces challenges common to agri-tech startups:

  • Adoption Barriers: Convincing farmers to adopt high-tech solutions can be slow.
  • Data Complexity: Translating vast microbiome data into actionable insights requires advanced AI and expertise.
  • Climate Variability: Soil microbiomes can vary greatly depending on weather and environmental conditions.

The company overcomes these challenges through user-friendly platforms, expert support, and continuous AI improvement.

Future Outlook

Biome Makers continues to innovate in agri-tech:

  • Geographic Expansion: Targeting more regions in Africa, Asia, and South America.
  • Enhanced AI Models: Improving predictive capabilities for crop yield and soil health.
  • Corporate Partnerships: Collaborating with agribusinesses and seed companies.
  • Sustainability Initiatives: Supporting regenerative agriculture practices and carbon footprint reduction.

For entrepreneurs, Biome Makers shows how cutting-edge science and AI can solve critical problems in traditional industries, creating both economic and environmental impact.


From a Spanish startup to a global agri-tech leader, Biome Makers is redefining farming through microbiome science. By providing actionable insights on soil health, the company empowers farmers to improve productivity sustainably. Its story highlights the potential of startups to transform agriculture with technology, data, and scientific innovation.

Written by

Leah Rosenfeld

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